PHILIPPS-UNIVERSITY OF MARBURG

Philipps-University of Marburg
Dept. of Gastroenterology
Baldingerstrasse
D-35043 Marburg
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Project leader

Prof. Dr. Thomas Gress

Philipps-University of Marburg

Phone: +49 6421 586 6460
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PD. Dr. Malte Buchholz

Philipps-University of Marburg

Phone: +49 6421 58 62714
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Project staff

Esther Buchholz

Philipps-University of Marburg

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Anja Krattenmacher

Philipps-University of Marburg

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Dr. Brajesh Kaistha

Philipps-University of Marburg

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Daniela Schumacher

Philipps-University of Marburg

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Lisa Fiedler

Philipps-University of Marburg

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Ramona Kreider

Philipps-University of Marburg

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Institute presentation

The medical faculty of the Philipps-University Marburg is one of the oldest medical faculties in Germany and has a strong record in translational medical research, with special focus on tumour biology and inflammation research. The division of Gastroenterology, headed by Prof. Dr. T.M. Gress, has a long-standing expertise in high-throughput genomic analyses of gastrointestinal tumours, functional analysis of candidate genes and characterisation of new therapeutic targets in pancreatic cancer, as well as characterisation of the crosstalk between cancer cells and stromal components in pancreatic tumours. Among others, our group has established the first expression profile of a solid tumour as early as 1996 (Gress et al., 1996), has provided global gene expression analyses of stellate cell populations from different organs (Buchholz et al., 2005a) and characterised pro-invasive effects of tumour cell-stellate cell interaction in pancreatic cancer (Neesse et al., 2007), as well as identified and characterised novel candidate genes with partly concurrent roles in tumour and immune cells (e.g. (Michl et al., 2005; Buchholz et al., 2006; Ripka et al., 2007; Weber et al., 2001)). In addition to our translational research tasks, we have a large clinical department which is a referral center for gastrointestinal tumours in central Germany. In this function, we are actively involved in large mono- and multicentric clinical trials for diagnosis, treatment and prevention of gastrointestinal tumours. Prof. Gress has ample experience in managing and coordinating multidisciplinary research projects. He has previously coordinated 4 EU-Projects, including the FP 6 integrated project “Novel molecular diagnostic tools for the prevention and diagnosis of pancreatic cancer (MolDiag-Paca)” ) as well as the pancreatic cancer translational genome research network (“PaCa-Net”) within the German National Genome Research Network initiative (NGFNplus), and is currently coordinating the FP 7 collaborative project "European Pancreatic Cancer-Tumour-Microenvironment Network" (EPC-TM-Net).  

  1. MolDiag-Paca
  2. PaCa-Net
  3. NGFNplus
  4. EPC-TM-net