Klinikum Rechts der Isar 
Technical University of Munich 
II. Medizinische Klinik 
Ismaninger Str. 22 
81675 Munich, Germany 

Project partner until October 31, 2015
Institute presentation

TUM-MED is a large university hospital (Klinikum rechts der Isar) with a prime focus in preclinical and clinical cancer research embedded in one of the largest biomedical environments in Germany. Thus, besides accumulation of many highly competitive preclinical and clinical/translational research groups at the hospital, there are multiple large research institutions focusing on cancer around including Max-Planck Institutes, Helmholtz Center and multiple Biotech companies.

In general, TUM-MED/Klinikum rechts der Isar is dedicated to cancer research with GI oncology and especially PDAC being the primary focus due to the scientific interest of both the Gastrointestinal and Surgical Department. At TUM-MED/GI Department, generation and characterisation of GEMM for endogenous PDAC has been performed for presumably longer times and in a by far more extensive way than anywhere else in Germany and competing with the largest research labs worldwide. The need for in-depth molecular characterisation has enabled the development of a highly sophisticated technical platform for genome-wide, multi-assay characterisation. Five years ago, one of the largest SFB initiatives (SFB824, “Imaging for the selection, monitoring and individualisation of cancer therapies”) started at TUM-MED with PDAC preclinical and translational/clinical imaging approaches being one of the central aims. Consequently, our group has established and has access to highly sophisticated multimodal imaging procedures including multiparametric MRT, PET with various tracers, molecular/optical imaging and high-resolution small animal ultrasound.